Chris Coe

Phone: 263-3550
Email: prilab@macc.wisc.edu
Office: Primate lab
Harlow Primate Lab

Professor
Ph.D. 1976, Downstate Medical Center, New York

My research is concerned with the influence of psychological and environmental factors on the immune system. Our studies with monkeys focus on how immune responses are affected at three points in the life span: prenatal, infancy, and old age. The focus on these three stages reflects my belief that they are times of heightened vulnerability. Our research in humans focuses on the link between emotions and immunity during times of challenge, such as exam week. Students who work with me learn how to conduct immunological assays and can choose to carry out studies on human or nonhuman primate models.

REPRESENTATIVE PUBLICATIONS

Coe, C.L. ( 2002). Neuroendocrine and behavioral influences on the immune system. In Becker, J.B., Breedlove, S.M., and Crews, E. (Eds.) Behavioral Endocrinology, MIT Press, Cambridge, MA, Pp. 373-408.

Liu, L.Y, Coe, C.L., Swenson, C.A., Kelley, E.A., Kita, H., & Busse, W.W. (2002). School examinations enhance airway inflammation to antigen challenge. American Journal of Respiratory and Critical Care Medicine 265: 1062-1067.

Coe, C.L.,Kramer, M., Kirschbaum, C. Netter, P. & Fuchs, E. (2002). Prenatal stress diminishes the cytokine response of leukocytes to endotoxin stimulation in juvenile monkeys. Journal Clinical Endocrinology and Metabolism 87: 675-681.

Rogers, S., Coe, C.L., & Karaszewski, J.W. (1999). Immune consequences of stroke and cerebral palsy in adults. Journal of Neuroimmunology, 91, 113-120.

Kang, D-H, Coe, C.L., McCarthy, D.O., & Ershler, W.B. (1996). Academic exams significantly impact immune responses, but not lung function in healthy and well-managed asthmatic adolescents. Brain, Behavior and Immunity. 10, 164-181.

Reyes, T.M. & Coe, C.L. (1996). Interleukin-1B differentially affects interleukin-6 and soluble interleukin-6 receptor in the blood and central nervous system of the monkey. Journal of Neuroimmunology, 66, 135-141.

Coe, C.L., Lubach, G.R., Karaszewski, J., & Ershler, W.B. (1996). Prenatal endocrine activation influences the postnatal development of immunity in the infant monkey. Brain, Behavior and Immunity, 10, 221-234.